Reinnervation post-Heart transplantation

Arrhythmia post heart transplantation

A variety of arrhythmias can occur after heart transplantation (HTx). Hearts selected to be donated for HTx should be in good condition and generally beat in sinus rhythm (SR). Absence or loss of SR after HTx can be due to any reason and can lead to serious hemodynamic problems. Ischemia reperfusion injury, unbalanced serum electrolytes and re-warming of cold myocardial tissue are known to init...

Sympathetic reinnervation and heart rate variability after cardiac transplantation.

BACKGROUND Heart rate variability is thought to measure autonomic modulation, but the relation has never been demonstrated directly in humans. AIM To test the hypothesis that increased low frequency heart rate variability reflects sympathetic reinnervation after cardiac transplantation. PATIENTS 24 cardiac transplant recipients at the time of routine surveillance coronary angiography two or...

Clinical determinants of ventricular sympathetic reinnervation after orthotopic heart transplantation.

BACKGROUND It has been demonstrated that ventricular sympathetic reinnervation after cardiac transplantation improves exercise performance. The extent of reinnervation increases with time but is variable. Little is known about other influencing factors. METHODS AND RESULTS Seventy-seven nonrejecting transplant recipients were cross-sectionally studied by PET with the catecholamine analogue C-...

Sympathetic reinnervation after heart transplantation, assessed by iodine-123 metaiodobenzylguanidine imaging, and heart rate variability.

OBJECTIVE Complete allograft denervation occurs during heart transplantation. Partial ventricular sympathetic reinnervation may develop one year or later after transplantation and can be measured with iodine-123-meta-iodobenziylguanidine (MIBG) uptake. Aim of this study was to assess sinus node sympathetic reinnervation measured with heart rate variability and ventricular sympathetic reinnervat...

Obstructive Sleep Apnea Induced Sinus Pause After Heart Transplantation: A Manifestation of Parasympathetic Reinnervation